Cancer Risk After Fat Transfer (CRAFT)

Project Title: Cancer Risk After Fat Transfer

Principal Investigators: Clara Lee, MD and Terry Myckatyn, MD

Clinical Coordinating Center: The Plastic Surgery Foundation

Data Coordinating Center: University of North Carolina-Chapel Hill

Participating Sites: MD Anderson Cancer Center, Memorial Sloan-Kettering Cancer Center, University of Chicago, and Washington University St. Louis

Project Description: In recent years, autologous fat grafting to the breast has become an increasingly popular plastic surgery technique used in breast cancer patients as part of reconstruction after breast conservation therapy or mastectomy. The procedure involves aspiration of fat from the patient's trunk or thighs and injection into the breast for augmentation or correction of contour deformities. Although the technique shows great promise, epidemiologic studies of the technique's oncologic safety have been lacking. To meet this need, this study is evaluating the relative risk of breast cancer recurrence after autologous fat grafting to the breast compared to not receiving fat grafting in a hospital-based population of stages I, II, and III breast cancer patients who had mastectomy with reconstruction.

Status: Data Collection Completed and Data Analysis is ongoing.

Publications/Resources