Grants Funded
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Research Abstracts
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
Synthesis Of A Tissue Engineered Periosteum
Principal Investigator
Bjorn Schonmeyr MD
Bjorn Schonmeyr MD
Year
2007
2007
Institution
Memorial Sloan-Kettering Cancer Center
Memorial Sloan-Kettering Cancer Center
Funding Mechanism
Basic Research Grant
Basic Research Grant
Focus Area
Tissue Engineering
Tissue Engineering
Abstract
Periosteal grafts can aid in fracture repair and promote healing of bone defects by providing bone progenitor cells and acting as a barrier to scar tissue. Unfortunately, these grafts have many of the same disadvantages as bone grafts (i.e. donor site morbidity and limited donor sites). We hypothesize that a tissue engineered construct composed of acellular human dermis (Alloderm) and bone progenitor cells would provide a periosteum-like material with the potential to deliver cells and growth factors thus promoting osseous regeneration.
Periosteal grafts can aid in fracture repair and promote healing of bone defects by providing bone progenitor cells and acting as a barrier to scar tissue. Unfortunately, these grafts have many of the same disadvantages as bone grafts (i.e. donor site morbidity and limited donor sites). We hypothesize that a tissue engineered construct composed of acellular human dermis (Alloderm) and bone progenitor cells would provide a periosteum-like material with the potential to deliver cells and growth factors thus promoting osseous regeneration.