The Plastic Surgery Foundation
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Grants We Funded

Grant Applicants for 2020 requested more than $4.1 million. The PSF Study Section Subcommittees of Basic and Translational Research and Clinical Research Evaluated 111 applications on the following topics:

The PSF awarded Research Grants totaling more than $860,000 to support 24 plastic surgery research proposals.

The American Society of Plastic Surgeons/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.

Research Abstracts

Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.

The Wnt Pathway and Biomaterials in Ssurgical Wound Regeneration

Principal Investigator
Stephen R. Sullivan MD, MPH, FACS

Year
2006

Institution
University of Washington

Funding Mechanism
Basic Research Grant

Focus Area
Wounds/Scar

Abstract
Adult wounds are repaired by proliferation and migration of multiple cell types that form a scar. Scar lacks skin appendages such as hair follicles, sweat glands and sebaceous glands; and dermal structure is contracted with variable collagen deposition. Undifferentiated cells can be found in the healing wound and can be recruited for skin structure regeneration rather than repair with scar. During embryogenesis, fate of undifferentiated cells are guided by multiple morphogens, including the Wnt gene family. The undifferentiated cells found in adult wounds can similarly be guided by Wnt genes transcription. The purpose of this application is to evaluate the effect of Wnt gene transcription on skin appendage regeneration of healing wounds. We hypothesize that Wnt gene expression will guide undifferentiated skin wound cells toward skin appendage regeneration during wound repair morphogenesis.