Grants Funded
Grant applicants for the 2024 cycle requested a total of nearly $3 million dollars. The PSF Study Section Subcommittees of Basic & Translational Research and Clinical Research evaluated more than 100 grant applications on the following topics:
The PSF awarded research grants totaling over $650,000 dollars to support more than 20 plastic surgery research proposals.
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Research Abstracts
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
Evaluation of CD18/11b Adhesion Molecule on Neutrophil Surface Membrane in Ischemia Reperfusion Injury
Richard Baynosa MD
2003
University of Nevada
Basic Research Grant
Microsurgery
The hypothesis of this project is that hyperbaric oxygen (HBO) inhibits ischemia-reperfusion (IR) induced neutrophil-I CAM adherence by preventing polarization of expressed surface CD 18 molecules. This HBO induced reduced adherence and polarization in neutrophils is due to a systemic increase in plasma nitric oxide (NO). The effect of HBO on systemic NO production is through up regulation of eNOS. Specific Objectives: To use a new quantitative method to evaluate the percent of CD 18-polarized and adherent neutrophils formed when reacted with Sham and IR plasma. To manipulate the percent ofCDl8-polarized and adherent neutrophils formed by treatment with hyperbaric oxygen a nitric oxide scavenger, and a nitric oxide synthase (NOS) inhibitor. This research should provide insight into the mechanisms of HBO in IR injury, which could significantly impact limb salvage and could have even broader implications in the treatment of IR injury in other organ systems.
Richard Baynosa, MD is an Assistant Professor of Plastic Surgery and the Associate Program Director for the plastic surgery integrated training program at the University of Nevada School of Medicine in Las Vegas. Dr. Baynosa received his undergraduate degree at UCLA followed by his medical degree from the UCSD School of Medicine. He completed an integrated plastic surgery residency at the University of Nevada School of Medicine including two years of basic science research primarily focused on hyperbaric oxygen mechanisms and ischemia-reperfusion injury. Dr. Baynosa has completed fellowship training in both hand and microsurgery as well as breast and aesthetic surgery. He then travelled to Belgium and Gent University Hospital to complete a fellowship in perforator flap and super-microsurgery under Philip Blondeel, MD. Dr. Baynosa is currently the Medical Director for the University Medical Center of Southern Nevada’s Advanced Wound Healing and Hyperbaric Medicine Center, where he serves on numerous local and national committees. He has authored several book chapters and articles and has presented his work at numerous local and national scientific meetings.