Grants Funded
Grant applicants for the 2024 cycle requested a total of nearly $3 million dollars. The PSF Study Section Subcommittees of Basic & Translational Research and Clinical Research evaluated more than 100 grant applications on the following topics:
The PSF awarded research grants totaling over $650,000 dollars to support more than 20 plastic surgery research proposals.
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Research Abstracts
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
Acellular Musculofascial Flap Matrix for Muscle Engineering
Qixu Zhang MD, PhD
2014
University of Texas M.D. Anderson Cancer Center
Pilot Research Grant
Tissue Engineering
Significant soft tissue loss due to severe traumatic events such as tumor resection often requires surgical reconstruction by means of autologous grafts such as muscle flaps. However, the restricted availability of qualitative autologous muscle flaps as well as the donor site morbidity significantly limits this approach. Engineered muscle flap grafts may offer a clinically relevant alternative to the autologous muscle flap. We propose to develop decellularized skeletal musclofascial flaps (DMFs) with a dominant vascular pedicle and then repopulate them with human adipose-derived stem cells (hASCs) and human umbilical vein endothelial cells (HUVECs) for pre-vascularization to improve the vascularization and survival of engineered muscle constructs after transplantation in vivo. The proposed work will be the first investigation that uses engineered skeletal musclofascial flap graft to replace autologous muscle flap. This research will contribute to biomedical science and will tremendously impact clinical musculofascial tissue reconstruction and regenerative medicine.
