Grants We Funded
Grant applicants for the 2021 cycle requested a total of over $3.3 million dollars. The PSF Study Section subcommittees of Basic & Translational Research and Clinical Research evaluated 106 grant applications on the following topics:
The PSF awarded research grants totaling more than $755,000 to support 25 plastic surgery research proposals.
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
Multilineage Stem Cell Therapy For Diabetic Wounds
Oren Tepper MD
New York University Medical Center
Basic Research Grant
Chronic non-healing wounds and ulcers account for up to 20% of all diabetic patient hospitalizations. Wound complications make a significant contribution to the growing cost of diabetes, which has reached an annual economic burden of $132 billion (NDIC. 2002). Currently a wide range of approaches are used to treat non-healing diabetic wounds, but most are strictly palliative. The following study offers a unique approach to wound healing by investigating the in vivo self-assembly of locally delivered mesenchymal stem cells (MSCs). Recent research has demonstrated that MSCs from the bone marrow traffic to healing wounds and are able to differentiate into mature endothelial cells to form new blood vessels. Previous work by our group and others suggests that bone marrow-MSC trafficking to diabetic wounds is impaired. The central hypothesis to be tested in this study is whether the delivery of non-diabetic (wildtype) lineage negative bone marrow cells to diabetic wounds will improve healing.