Grants We Funded
Grant applicants for the 2022 cycle requested a total of over $2.9 million dollars. The PSF Study Section subcommittees of Basic & Translational Research and Clinical Research evaluated 115 grant applications on the following topics:
The PSF awarded research grants totaling almost $550,000 to support 19 plastic surgery research proposals.
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
Optimizing Tendon Repair Using Photochemical Tissue Bonding
Jonathan Winograd MD
Massachusetts General Hospital
Basic Research Grant
Photochemical Tissue Bonding (PTB) is a new technique in which a photosensitizing dye is irradiated with visible laser light to create covalent bonds between tissue surfaces. Unlike conventional laser welding that generates heat in the tissue; PTB is a non thermal system that initiates immediate chemical bonds without collateral damage to surrounding tissues. This technique has been used experimentally in a number of tissue repair models including corneal lesion repair, nerve repair and enhancement of skin graft adhesion. It has also been used with success in the repair of achilles tendon rupture in a rat model. PTB repair of peripheral nerve also demonstrated improved functional outcome following augmentation of the technique with an amnion wrap.
Dr. Winograd is a reconstructive plastic surgeon at Massachusetts General Hospital. He completed both his general and plastic surgery training at Johns Hopkins Hospital including a two year research fellowship in the Plastic Surgery Research Laboratory. He then went on to do an additional year of fellowship training in Hand and Microsurgery at Washington University in Saint Louis in the Division of Plastic Surgery. His research focus has been the improvement of outcomes following microsurgical repair of peripheral nerve injuries. With grant support from the Plastic Surgery Foundation and ASPS, as well as the Academic Scholar program of the American Association of Plastic Surgeons, he has developed a translational research program which investigates the use of photochemical tissue bonding to decrease scarring at neurorrhaphy sites and better isolate the regenerative environment necessary to promote optimal neural regeneration. He is currently funded by the Department of Defense to further investigate the benefits of this technique combined with large gap peripheral nerve injuries and nerve grafting. Most recently, with the current grant support from PSF, the photochemical tissue bonding is being used to improve microsurgical repair of blood vessels, with the added implementation of a dissolvable glass stent to aid in the technical performance and stabilization of the anastomosis.