Grants Funded
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Research Abstracts
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
Real Time, in Situ Microimaging of Peripheral Nerve Injury
Principal Investigator
Francis Henry MD
Francis Henry MD
Year
2007
2007
Institution
Massachusetts General Hospital
Massachusetts General Hospital
Funding Mechanism
Basic Research Grant
Basic Research Grant
Focus Area
Peripheral Nerve
Peripheral Nerve
Abstract
A method by which the internal neural state could be assessed, in terms of architectural preservation, would allow for an early grading of the level of injury, a more rapid and accurate determination of the prognosis, and an earlier, more informed decision about whether to continue observation or to proceed with nerve reconstruction. The objective of this study is to assess the ability of a novel high resolution imaging technique (Coherent Anti-stokes Raman Scattering Microscopy) to categorize peripheral nerve damage, and to monitor the recovery process of a damaged nerve. Features in these images will be compared with known anatomy and histology in real time in order to assess the ability of this technology to evaluate peripheral nerve damage. Changes in these features will be used to observe regrowth or atrophy of the nerves.
A method by which the internal neural state could be assessed, in terms of architectural preservation, would allow for an early grading of the level of injury, a more rapid and accurate determination of the prognosis, and an earlier, more informed decision about whether to continue observation or to proceed with nerve reconstruction. The objective of this study is to assess the ability of a novel high resolution imaging technique (Coherent Anti-stokes Raman Scattering Microscopy) to categorize peripheral nerve damage, and to monitor the recovery process of a damaged nerve. Features in these images will be compared with known anatomy and histology in real time in order to assess the ability of this technology to evaluate peripheral nerve damage. Changes in these features will be used to observe regrowth or atrophy of the nerves.