Grants We Funded
Grant applicants for the 2022 cycle requested a total of over $2.9 million dollars. The PSF Study Section subcommittees of Basic & Translational Research and Clinical Research evaluated 115 grant applications on the following topics:
The PSF awarded research grants totaling almost $550,000 to support 19 plastic surgery research proposals.
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
Reduction of Scarring In-vivo Using Novel Antisense Therapy
Zol Kryger MD
Basic Research Grant
Excessive and hypertrophic scarring are problems that continue to confront surgeons. Clinical and experimental attempts to reduce scarring have met with limited success. There remains a need for the development of an effective anti-scarring therapy. The purpose of this project is to use a molecular therapy approach to reduce scar formation in a rabbit ear model of hypertrophic scarring. We hypothesize that specific inhibition of various gene products integral to the scarring process, namely, TGFbeta-l, TGFbeta-2, TGFbeta receptor I, and CTGP, will cause a reduction in cutaneous scarring. We aim to achieve this goal using antisense oligonucleotides that block the mRNA of these genes.