The Plastic Surgery Foundation
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Grants We Funded

Grant applicants for the 2023 cycle requested a total of nearly $4 million dollars. The PSF Study Section Subcommittees of Basic & Translational Research and Clinical Research evaluated nearly 140 grant applications on the following topics:

The PSF awarded research grants totaling over $1 million dollars to support nearly 30 plastic surgery research proposals.

ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.

Research Abstracts

Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.

Reduction of Scarring In-vivo Using Novel Antisense Therapy

Principal Investigator
Zol Kryger MD


Northwestern University

Funding Mechanism
Basic Research Grant

Focus Area
Technology Based

Excessive and hypertrophic scarring are problems that continue to confront surgeons. Clinical and experimental attempts to reduce scarring have met with limited success. There remains a need for the development of an effective anti-scarring therapy. The purpose of this project is to use a molecular therapy approach to reduce scar formation in a rabbit ear model of hypertrophic scarring. We hypothesize that specific inhibition of various gene products integral to the scarring process, namely, TGFbeta-l, TGFbeta-2, TGFbeta receptor I, and CTGP, will cause a reduction in cutaneous scarring. We aim to achieve this goal using antisense oligonucleotides that block the mRNA of these genes.