The Plastic Surgery Foundation
Log In Donate Now
 

Grants We Funded

In 2019, The Plastic Surgery Foundation (The PSF) awarded 33 investigator-initiated projects and allocated $891,274 to support the newest, clinically relevant research in plastic surgery.

The American Society of Plastic Surgeons/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.

Research Abstracts

Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area, or PSF funding mechanism.

Reduction of Scarring In-vivo Using Novel Antisense Therapy

Principal Investigator
Zol Kryger MD

Year
2005

Institution
Northwestern University

Funding Mechanism
Basic Research Grant

Focus Area
Technology Based

Abstract
Excessive and hypertrophic scarring are problems that continue to confront surgeons. Clinical and experimental attempts to reduce scarring have met with limited success. There remains a need for the development of an effective anti-scarring therapy. The purpose of this project is to use a molecular therapy approach to reduce scar formation in a rabbit ear model of hypertrophic scarring. We hypothesize that specific inhibition of various gene products integral to the scarring process, namely, TGFbeta-l, TGFbeta-2, TGFbeta receptor I, and CTGP, will cause a reduction in cutaneous scarring. We aim to achieve this goal using antisense oligonucleotides that block the mRNA of these genes.