The Plastic Surgery Foundation
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Grants We Funded

Grant applicants for the 2021 cycle requested a total of over $3.3 million dollars. The PSF Study Section subcommittees of Basic & Translational Research and Clinical Research evaluated 106 grant applications on the following topics:

The PSF awarded research grants totaling more than $755,000 to support 25 plastic surgery research proposals.

ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.

Research Abstracts

Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.

Biologic Brachytherapy: Targeted Delivery of Antimicrobial Peptides to Treat Osteomyelitis via Ex-vivo Gene Therapy of Microvascular Free Flaps

Principal Investigator
Shadi Ghali MD

Year
2005

Institution
New York University Medical Center

Funding Mechanism
Basic Research Grant

Focus Area
Technology Based

Abstract
Some of the most challenging problems in plastic surgery include the management of chronically infected wounds in vasculopathic patients and the reconstruction of large, contaminated, complex defects with exposed bone and/or hardware following lower limb trauma. Microvascular free tissue transfer is often required to fill resulting soft tissue and osseous defects. Free flaps provide a reconstructive role by transferring well vascularized tissue to deficient areas. As they have an intact microvasculature supplied by an afferent artery and efferent vein, they have the potential to provide an additional therapeutic role. We intend to exploit the vascular properties of free flaps to deliver targeted genes capable of producing therapeutic proteins. This dual therapeutic as well as reconstructive role holds enormous potential in the field of reconstructive surgery and provides a framework for expanding the efficacy of free flaps.