Grants We Funded
Grant applicants for the 2023 cycle requested a total of nearly $4 million dollars. The PSF Study Section Subcommittees of Basic & Translational Research and Clinical Research evaluated nearly 140 grant applications on the following topics:
The PSF awarded research grants totaling over $1 million dollars to support nearly 30 plastic surgery research proposals.
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Research Abstracts
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
In Vivo Trafficking of Adipose-Derived Multipotent Mesenchymal Cells to Cutaneous Wound Sites
Edward Park MD
2004
Stanford University
Basic Research Grant
Tissue Engineering
Bone marrow stem cells have been found to play a critical role in orchestrating the healing process. The transdifferentiation of multipotent cells has been studied by systemically delivering these cells in various injury models. Recently, an alternative mesenchymal source for progenitor cells has been isolated from adipose tissue. Adipose-derived multipotent mesenchymal cells (AdMMCs) have the capacity to differentiate into various cell lineages; however, their potentially important role in cutaneous wound healing has not been well characterized. In this proposal, we hypothesize that systemically administered AdMMCs will preferentially traffic to skin wound sites and facilitate repair. In Specific Aim #1, the homing pattern of these cells to cutaneous wound sites using a novel in vivo bioluminescence imaging technique will be performed. In Specific Aim #2, utilizing this luminescent modality, we will study the migration of AdMMCs in a mouse injury model by adding specific growth factors to the skin wound site. Engraftment of AdMMCs will be confirmed by immunolocalization, and wound area will be used to quantitate repair rate. We believe AdMMCs are a novel progenitor cell source for clinical transplantation in cutaneous wounds that may enhance wound repair and also be useful for tissue engineering.