Grants We Funded
Grant applicants for the 2022 cycle requested a total of over $2.9 million dollars. The PSF Study Section subcommittees of Basic & Translational Research and Clinical Research evaluated 115 grant applications on the following topics:
The PSF awarded research grants totaling almost $550,000 to support 19 plastic surgery research proposals.
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
ADSC Potentiates Tissue Reorganization/Repair--Radiated Expansion
Nada Berry MD
Southern Illinois University School of Medicine
National Endowment for Plastic Surgery Grant
Breast (Cosmetic / Reconstructive), Tissue Engineering
Tissue expansion and implants are widely used for breast reconstruction after mastectomy; however, clinical application has been greatly limited by adjuvant radiotherapy. Progressive damage of the overlying skin not only leads to low expansion efficiency, but also poor aesthetics and increased complications. Identifying a therapy that may be tissue protective or enhance tissue regeneration during expansion in spite of radiotherapy may decrease the poor sequelae encountered by these patients during breast reconstruction. Interest in adipose-derived mesenchymal stem cells (ADSC) in promoting tissue regeneration is currently under investigation. However, its effect on skin regeneration during tissue expansion in the setting of a radiated field has yet to be determined. We hypothesize that ADSC transplantation will decrease tissue damage and enhance the efficiency of tissue expansion in animals treated with radiotherapy. To test this hypothesis, a rat model will be used, wherein tissue expansion will be undertaken in the setting of irradiation. ADSCs will be transplanted into the experimental group after radiation. The effects on tissue regeneration will be measured by evaluating ADSC differentiation into various regenerative skin components and quantifying ADSC paracrine secretion of growth hormones.
Nada Berry, MD is an Assistant Professor in the Division of Plastic Surgery at Southern Illinois University School of Medicine in Springfield, IL. She received her medical degree from Indiana University School of Medicine in Indianapolis, IN and previously completed a degree in biology from Chadron State College in Chadron, NE. Dr. Berry completed her plastic surgery residency at the Southern Illinois University School of Medicine in Springfield, IL. She continued her training at Mayo Clinic in Rochester, MN in a one-year hand fellowship. Dr. Berry is a member of the American Burn Association, Sangamon County Medical Society and the Illinois State Medical Society. Dr. Berry has given multiple national and regional presentations. She has also authored multiple book chapters and articles.