The Plastic Surgery Foundation
Log In Donate Now
 

Grants We Funded

Grant applicants for the 2021 cycle requested a total of over $3.3 million dollars. The PSF Study Section subcommittees of Basic & Translational Research and Clinical Research evaluated 106 grant applications on the following topics:

The PSF awarded research grants totaling more than $755,000 to support 25 plastic surgery research proposals.

ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.

Research Abstracts

Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.

Effect Of Radiation On Tissue For Delayed Breast Reconstruction

Principal Investigator
Adeyiza Momoh MD

Year
2012

Institution
The Regents of the University of Michigan

Funding Mechanism
Pilot Research Grant

Focus Area
Breast (Cosmetic / Reconstructive), General Reconstructive

Abstract
In the setting of post-mastectomy radiation therapy delayed autologous reconstruction, favored by many attempts to avoid complications encountered with radiating the immediately reconstructed breast. The timing of delayed reconstruction is however not known. The goal of this proposal is to study the gross, structural and vascular changes in radiated mastectomy skin in addition to possible structural and flow changes of the underlying internal mammary vessels over time. We plan to use these objective findings as a basis for determining an ideal time frame for delayed autologous breast reconstruction. Sequential mastectomy skin specimens will be obtained from 20 patients undergoing post-mastectomy radiation therapy over a 12 month period and these specimens will be evaluated histologically. These same patients will also undergo serial examinations and photographic documentation of gross skin changes. Skin perfusion will be assessed by laser Doppler imaging and internal mammary vessel structure, and flow characteristics will be assessed by color Doppler sonography. Based on these studies, we will elucidate short and long term changes in radiated breast skin, showing inflammatory, structural and perfusion patterns that can be correlated with optimal conditions for reconstruction. There is also potential for improved outcomes of delayed breast reconstruction by decreasing the number of reconstructions performed too soon after completion of radiation.

Biography
Adeyiza Momoh, MD received his medical education from the Northwestern University Feinberg School of Medicine in Chicago. He then completed a combined general surgery and plastic surgery residency training at the Baylor College of Medicine in Houston. He went on to a microsurgery fellowship at the Harvard Medical School, Beth Israel Deaconess Medical Center in Boston. He is now on the faculty of the Section of Plastic Surgery at the University of Michigan in Ann Arbor where he focuses on clinical interests in microsurgical breast reconstruction and research interests in breast reconstruction outcomes. He has a particular interest in better understanding the interplay between radiation therapy and autologous breast reconstruction outcomes.