Grants We Funded
Grant applicants for the 2022 cycle requested a total of over $2.9 million dollars. The PSF Study Section subcommittees of Basic & Translational Research and Clinical Research evaluated 115 grant applications on the following topics:
The PSF awarded research grants totaling almost $550,000 to support 19 plastic surgery research proposals.
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Research Abstracts
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
Point of Care Detection & Prevention of Muscle Fibrosis In Critical Care Patients
Geoffrey Hespe MD
2020
The Regents of the University of Michigan
Research Fellowship
General Reconstructive, Wounds / Scar
Project Summary: Muscle fibrosis can occur following trauma, muscle flap surgery, radiation or tourniquet use resulting in significant loss of function. Here we will validate novel treatment strategies to prevent muscle fibrosis and stimulate muscle regeneration. Using validated muscle fibrosis models, we will investigate the role macrophage derived TGF-beta1 plays in the development of this process. In addition to elucidating the key cells and pathways behind muscle fibrosis, we will evaluate high frequency spectral ultrasound imaging as a way to provide early detection and guide treatment initiation. Through a better understanding of muscle fibrosis and early detection, this study will benefit surgeons and clinicians by reducing the morbidity of muscle fibrosis through precise image guided interventions. Impact Statement: Muscle fibrosis can occur following trauma, muscle flap surgery, radiation or tourniquet use resulting in significant loss of function. Here we will validate novel treatment strategies to prevent muscle fibrosis and stimulate muscle regeneration. Using validated muscle fibrosis models, we will investigate the role macrophage derived TGF-beta1 plays in the development of this process. In addition to elucidating the key cells and pathways behind muscle fibrosis, we will evaluate high frequency spectral ultrasound imaging as a way to provide early detection and guide treatment initiation. Through a better understanding of muscle fibrosis and early detection, this study will benefit surgeons and clinicians by reducing the morbidity of muscle fibrosis through precise image guided interventions.
