Grants We Funded
Grant applicants for the 2022 cycle requested a total of over $2.9 million dollars. The PSF Study Section subcommittees of Basic & Translational Research and Clinical Research evaluated 115 grant applications on the following topics:
The PSF awarded research grants totaling almost $550,000 to support 19 plastic surgery research proposals.
ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.
Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.
Simultaneous renal and vascularized bone allotransplantation
Gerhard Mundinger MD
University of Maryland, Baltimore
Composite Tissue Allotransplantation
Vascularized bone marrow (VBM) transplantation allows for the uninterrupted transfer of donor bone marrow cells within the preserved donor microenvironment, and is considered to be superior to cellular bone marrow transplantation alone in the induction of tolerance and reduction of immunosuppression requirements in animal models. Despite promising results with isolated VBM allotransplantation and transplantation of VBM contained in composite tissue limb allografts, no study to date has investigated the cotransplantation of isolated VBM with a solid organ. This proposal aims to develop a rat model of simultaneous isolated femoral VBM/renal cotransplantation before exploring the ability of cotransplanted VBM to support renal allograft survival and function with full immunosuppression. The proposed research will then explore the ability of cotransplanted VBM to induce chimersim and tolerance once immunosuppression is withdrawn. If successful, this work would support research efforts in non-human primates exploring VBM/solid organ cotransplantation, as well as human clinical trials in patients undergoing renal transplantation.
Dr. Mundinger was born in Washington, D.C, and grew up in Jackson, Mississippi. He completed his undergraduate studies at the University of Michigan, majoring in Biology, Environmental Policy, and Resource Ecology. He attended medical school at Johns Hopkins University, during which time he completed a year of research in the Surgery Branch and Division of Pathology at the National Institutes of Health under a Clinical Research Training Program fellowship. He received an American Association for Cancer Research Busch Scholar-in-Training Award for his work on reverse phase protein microarray in 2007. Subsequently, he began residency in the joint Johns Hopkins Hospital/University of Maryland integrated plastic surgery residency program. Having completed a year of research investigating the immunobiology of non-human primate facial and fibular composite tissue allotransplants under the mentorship of Dr. Eduardo D. Rodriguez, he will explore tolerogene