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Grants We Funded

Grant applicants for the 2023 cycle requested a total of nearly $4 million dollars. The PSF Study Section Subcommittees of Basic & Translational Research and Clinical Research evaluated nearly 140 grant applications on the following topics:

The PSF awarded research grants totaling over $1 million dollars to support nearly 30 plastic surgery research proposals.

ASPS/PSF leadership is committed to continuing to provide high levels of investigator-initiated research support to ensure that plastic surgeons have the needed research resources to be pioneers and innovators in advancing the practice of medicine.

Research Abstracts

Search The PSF database to have easy access to full-text grant abstracts from past PSF-funded research projects 2003 to present. All abstracts are the work of the Principal Investigators and were retrieved from their PSF grant applications. Several different filters may be applied to locate abstracts specific to a particular focus area or PSF funding mechanism.

Cranial Particulate Graft vs. Bone-Dust for Inlay Cranioplasty

Principal Investigator
Arin Greene MD

Year
2009

Institution
Children's Hospital Boston

Funding Mechanism
Pilot Research Grant

Focus Area
Cranio / Maxillofacial / Head and Neck, Tissue Engineering

Abstract
Repair of calvarial defects in children is difficult because the supply of autologous bone is limited, and alloplastic substances are not advocated because they inhibit cranial growth. Although split cranial bone is the preferred material to correct cranial defects in children, it cannot be harvested in children less than 6 years of age. In order to overcome the limited supply of autologous bone graft in young children, bone-dust produced by high-speed drilling and particulate bone obtained with a hand-driven brace and bit have been used to fill cranial defects. The purpose of this project is to test the hypothesis that autologous cranial particulate bone graft is superior to bone-dust for inlay cranioplasty because it is osteoconductive, osteoinductive, and osteogenic.

The specific aims of this project are:

1. To compare the ossification, osseointegration and vascularization of inlay autologous cranial particulate bone and bone-dust.

2. To determine the osteogenic, osteoinductive and osteoconductive properties of cranial particulate bone and bone-dust.

Biography
Dr. Greene’s research background is in the field of angiogenesis. He trained in the Harvard Combined Plastic Surgery Program and then completed a fellowship in Craniofacial/Pediatric Plastic Surgery at Children’s Hospital Boston. His basic science and clinical research is focused on vascular anomalies, lymphedema, and cranioplasty.